Never heard this before. Do you mind explaining why?
Prime works by binding to the ammonia and rendering it harmless to your aquarium inhabitants. While the Prime is bound to your ammonia, it allows the biological filter in your tank to easily digest the ammonia. Because of this, Prime is a great product to use while cycling because it will promote the growth of beneficial bacteria in your tank. Since Prime is known as a "reducing agent," overdosing will lead to binding of oxygen, reducing the amount of useable oxygen in the tank. You should not use more than 5x the recommended dosage every 48 hours. This dosage should be sufficient to alleviate ammonia and will be safe for your tank.